diff --git a/contrib/guix/manifest.scm b/contrib/guix/manifest.scm
index 910a9dd6f65..d493eab14a3 100644
--- a/contrib/guix/manifest.scm
+++ b/contrib/guix/manifest.scm
@@ -239,5 +239,5 @@ chain for " target " development."))
           ((string-contains target "-linux-")
            (list (make-bitcoin-cross-toolchain target)))
           ((string-contains target "darwin")
-           (list clang-toolchain-8 binutils imagemagick libtiff librsvg font-tuffy cmake xorriso))
+           (list clang-toolchain-10 binutils imagemagick libtiff librsvg font-tuffy cmake xorriso))
           (else '())))))